Abstract
Laparoscopic cholecystectomy is the gold standard therapeutic approach for the treatment of acute cholecystitis. However, there are times when patient are deemed poor surgical candidates because of Pre-existing conditions or a current diagnosis causing hemodynamic instability and/or coagulopathies. In lieu of Laparoscopic or open cholecystectomies because of the high risk the alternative is the placement of Percutaneous cholecystostomy tube (PCT) via Interventional Radiology(IR) given the lower risk of morbidity. The objective of this study was to take an in depth analysis of the clinical outcomes and the utilization of PCT for patients diagnosed with acute cholecystitis but deemed poor surgical candidates. This was a retrospective clinical study of 121 patients who were unfit to undergo surgery at the time of diagnosis of acute cholecystitis and had PCT placed between November 2012-July 2020. During this time period there were 4596 cholecystectomies done, which shows that about 2.63% underwent PCT placement.. Patients whom underwent treatment for acute cholecystitis with PCT had drain in place for an average of 54.6 days, and resolution of symptoms secondary to biliary decompression and targeted antibiotic therapy. PCT is an effective and safe initial treatment in patients with acute cholecystitis that are acutely ill and not stable to undergo a cholecystectomy with biliary decompression & targeted antibiotic therapy to alleviate symptoms. At time it may even considered as the definitive treatment in patients who are deemed high risk and/or too frail to undergo cholecystectomy.
Full text article
References
2. Ambe, P., Kaptanis, S., Papadakis, M., Weber, S., Jansen, S. and Zirngibl, H., 2016. The Treatment of Critically Ill Patients With Acute Cholecystitis. Deutsches Aerzteblatt Online, 113, pp.545-551.
3. Saddetin Er, Berkem H, Özden S, et al. Clinical course of percutaneous cholecystostomies: A cross-sectional study. World J Clin Cases. 2020;8(6):1033-1041. doi:10.12998/wjcc.v8.i6.1033
4. Baron, T., Grimm, I. and Swanstrom, L., 2020. Interventional Approaches To Gallbladder Disease New England Journal of Medicine. Available at: https://www.nejm.org/doi/pdf/10.1056/NEJMra1411372
5. Horn T, Christensen SD, Kirkegård J, Larsen LP, Knudsen AR, Mortensen FV. Percutaneous cholecystostomy is an effective treatment option for acute calculous cholecystitis: a 10-year experience. HPB (Oxford) 2015:17:32
6. Winbladh, A., Gullstrand, P., Svanvik, J. and Sandström, P., 2009. Systematic review of cholecystostomy as a treatment option in acute cholecystitis. HPB, 11(3), pp.183-193.
7. Macchini, D., Degrate, L., Oldani, M., Leni, D., Padalino, P., Romano, F. and Gianotti, L., 2016. Timing of percutaneous cholecystostomy tube removal: systematic review. Edizioni minerva medica, 71(6), pp.415-424.
8. Blanco, P. and Do Pico, J., 2015. Ultrasound-guided percutaneous cholecystostomy in acute cholecystitis: case vignette and review of the technique. Journal of Ultrasound, 18(4), pp.311-315.
9. Hadi, Y. B., Muhammad, W., Umer, H. M., Alam, A., Alvi, A., Khan, M. R., Shariff, A. H., 2016. Bacterobilia in acute cholecystitis: bile cultures' isolates. JPMA: Journal of Pakistan Medical Association, 66(10), S-50-S-52.
10. A Suri, M Yasir, M Kapoor, A Aiman, A Kumar., 2009 Prospective Study On Biliary Bacteriology In Calcular Disease Of The Gall Bladder And The Role Of Common Newer Antibiotics. The Internet Journal of Surgery, 22 (2), pp.1-5.
11. Alvino DML, Fong ZV, McCarthy CJ, et al. Long-Term Outcomes Following Percutaneous Cholecystostomy Tube Placement for Treatment of Acute Calculous Cholecystitis. J Gastrointest Surg. 2017;21(5):761-769. doi:10.1007/s11605-017-3375-4
12. Altieri MS, Bevilacqua L, Yang J, et al. Cholecystectomy following percutaneous cholecystostomy tube placement leads to higher rate of CBD injuries. Surg Endosc. 2019;33(8):2686-2690. doi:10.1007/s00464-018-6559-4
13. Schlottmann F, Gaber C, Strassle PD, Patti MG, Charles AG. Cholecystectomy Vs. Cholecystostomy for the Management of Acute Cholecystitis in Elderly Patients. J Gastrointest Surg. 2019;23(3):503-509. doi:10.1007/s11605-018-3863-1
14. Colonna AL, Griffiths TM, Robison DC, et al. Cholecystostomy: Are we using it correctly?. Am J Surg. 2019;217(6):1010-1015. doi:10.1016/j.amjsurg.2019.04.002