LUPUS OR NOT LUPUS? That is the question: a case report about a full-house GNMP.

Abstract

Lupus nephritis diagnosis is defined by the EULAR and ACR lupus classification criteria and its diagnosis is usually easy when the SLE (Systemic Lupus Erythematosus) is known, but it may be challenging when the kidney manifestation is inaugural with no other organ envolvement especially no immunological criteria. We report the case of a 43 years old patient admitted for impure nephrotic syndrome with macroscopic hematuria and renal failure. The renal biopsy showed the aspect of a glomerulonephritis mesangio-proliferative (GNMP) with a full-house aspect in immunofluorescence. the presence of specific signs of Lupus nephritis helped retain the diagnosis of Lupus. And the positivity of the immunological assessment during the follow-up confirmed it.