A, A1, H (A2) and B red blood cell antigens in blood donor

Ir.  Tsintsadze; L.  Akhvlediani; S.  Tskvitinidze; R.  Khukhunaishvili; M.  Koridze; T.  Koiava; R.  Loria; M.   Nagervadze

doi:10.15520/mcrr.v3i5.97

Ir. Tsintsadze ⁽¹⁾ , L. Akhvlediani ⁽²⁾ , S. Tskvitinidze ⁽³⁾ , R. Khukhunaishvili ⁽⁴⁾ , M. Koridze ⁽⁵⁾ , T. Koiava ⁽⁶⁾ , R. Loria ⁽⁷⁾ , M. Nagervadze ⁽⁸⁾

(1) Biology department, Batumi Shota Rustaveli State University, Georgia , Russian Federation

(2) Medical Faculty, Bau International University, Batumi, Georgia , Russian Federation

(3) Biology department, Batumi Shota Rustaveli State University, Georgia , Russian Federation

(4) Biology department, Batumi Shota Rustaveli State University, Georgia , Russian Federation

(5) Biology department, Batumi Shota Rustaveli State University, Georgia , Russian Federation

(6) Biology department, Batumi Shota Rustaveli State University, Georgia , Russian Federation

(7) Clinical diagnostic laboratory of Iris Borchashvili Health Center Medina, Georgia , Russian Federation

(8) Biology department, Batumi Shota Rustaveli State University, Georgia , Russian Federation

https://doi.org/10.15520/mcrr.v3i5.97

Issue
Vol. 3 No. 5 (2020): Journal of Medical Care Research and Review

Submitted
May 13, 2020

Published
May 14, 2020

Keywords:

Blood, antigens, erythrocyte, distribution, donors.

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Abstract

154 blood samples were tested for the antigens of red blood cell groups. The samples were provided from the Hematology laboratory of “Iris Borchashvili Health Center Medina Ltd” (on of the biggest local hospital). The laboratory analysis was conducted in the immunogenetic laboratory of Batumi Shota Rustaveli State University. The immunoserological express method was used for screening the erythrocyte blood group antigens. We used the following monoclonal antibodies: anti- A,-A1,- H (A2),-B,-AB. A reverse method was also used for the study. The distribution of the ABO group system in the studied donor population is as follows: O > A > B> AB. Among the studied blood donors, antigen A occurs in 61 donors, antigen B in 23 cases, and H (A2) antigen was found in 82 donors. Accordingly, H (A2) antigen is found at a frequency of 53.24%, the distribution of antigen A is 39.1%, and antigen B occurs with the frequency of 14.93%. The vast majority of donors of the phenotypic group A (II) contain A1. A2(H) antigens were detected only in single cases. As for the phenotypic group AB (IV), only subgroup A1 antigen was found.