ANTIDIABETIC POTENTTIAL OF A NOVEL POLYHERBAL PREPARATION IN ALBINO RATS
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Abstract
The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus using streptozotocin in normal Albino wistar rats and study the antidiabetic activity of polyherbal formulation (FD1) by comparison of levels of glucose between normal and diabetic rats. Hypoglycemic agents from natural and synthetic sources are available for treatment of diabetes. Indian medicinal plants have been found to be useful to successfully manage diabetes. The effect of ethanolic extracts of leaves of Alstonia scholaris, Heartwood of Pterocarpus marsupium, Heartwood of Embelia ribes investigated in normal, and streptozotocin induced diabetic rats. Significant anti diabetic activity was exhibited by the poly herbal formulation. Serum glucose level was found to be increased in diabetic animals. Treatment with the polyherbal Preparation 200 mg/kg body wt for 15 days in diabetic animals has shown significant decrease in serum glucose levels in comparison to control animals. The study reported that polyherbal preparation at a dose of 200 mg/kg body weight showed significant decline in blood glucose level
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